Aminooxy-PEG2-alcohol
Aminooxy-PEG2-alcohol is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Aminooxy-PEG2-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].
Product Specifications
CAS Number
185022-12-2
UNSPSC
12352203
Hazard Statement
H302-H315-H318-H335
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aminooxy-peg2-alcohol.html
Solubility
10 mM in DMSO
Smiles
NOCCOCCO
Molecular Formula
C4H11NO3
Molecular Weight
121.14
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Marek Kwiatkowski. Conjugates of biologically active molecules to functionalized polymers. WO2013186632A2.|[2]Murray BS, et al. Reactive thermoresponsive copolymer scaffolds. Chem Commun (Camb) . 2010 Dec 7;46 (45) :8651-3.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Non-cleavable Linker; PEG Linkers
Available Sizes
Frequently Asked Questions
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