Diclofenac acyl glucuronide
Diclofenac acyl glucuronide (D-1-O-G) is a major bile metabolite directly involved in small intestinal ulceration in rats[1].
Product Specifications
CAS Number
[64118-81-6]
Product Name Alternative
D-1-O-G
UNSPSC
12352005
Hazard Statement
H301
Target
Drug Metabolite; Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/diclofenac-acyl-glucuronide.html
Purity
98.34
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@H](OC(CC2=CC=CC=C2NC3=C(Cl)C=CC=C3Cl)=O)O[C@H](C(O)=O)[C@@H](O)[C@@H]1O
Molecular Formula
C20H19Cl2NO8
Molecular Weight
472.27
Precautions
H301
References & Citations
[1]Seitz S, et al. Diclofenac acyl glucuronide, a major biliary metabolite, is directly involved in small intestinal injury in rats. Gastroenterology. 1998 Dec;115 (6) :1476-82.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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