Myristoyl coenzyme A
Myristoyl coenzyme A is a myristoylated coenzyme A (CoA) . Myristoylation is an essential process in viruses and is generally controlled by N-myristoyltransferase (NMT) . And NMT is more active in colon epithelial tumors than in normal cells. Reduced Ccoenzyme A (CoA) is known to be a key regulator of NMT activity, whereas oxidized CoA does not allow NMT to promote myristoylation. Myristoyl coenzyme A blocks the demyristoylation process and has potential anticancer and antiviral mechanisms.
Product Specifications
CAS Number
3130-72-1
Product Name Alternative
14:0 Coenzyme A; S-Tetradecanoate-CoA; S-Tetradecanoate-coenzyme A
UNSPSC
12352204
Hazard Statement
H302-H315-H319-H335
Target
Endogenous Metabolite
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/myristoyl-coenzyme-a.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(CCCCCCCCCCCCC)=O)=O)=O)(O)=O)(O)=O)O[C@H]1N2C=NC3=C(N)N=CN=C32
Molecular Formula
C35H62N7O17P3S
Molecular Weight
977.89
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Enzyme
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Frequently Asked Questions
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