Mal-VC-PAB-ABAEP-Azonafide
Mal-VC-PAB-ABAEP-Azonafide is a agent-linker conjugate for ADC with with potent antitumor activity by using Azonafide (a cytotoxin), linked via the ADC linker Mal-VC-PAB[1].
Product Specifications
CAS Number
[2259318-48-2]
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mal-vc-pab-abaep-azonafide.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCN2CCN(CCNC(C3=CC=C(NC(OCC4=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN5C(C=CC5=O)=O)=O)=O)=O)C=C4)=O)C=C3)=O)CC2)C6=C7C(C(OC)=CC=C7C1=O)=CC8=CC=CC=C68
Molecular Formula
C61H71N11O12
Molecular Weight
1150.28
References & Citations
[1]LANNUTTI, Brian, et al. ROR1 ANTIBODY IMMUNOCONJUGATES. WO 2018/237335 Al.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Curated Selection
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