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Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA

Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA is a double claevable 3-unit and 4-unit PEG linker for antibody-agent-conjugation (ADC) . Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA also is a PROTAC linker that can be used in the synthesis of PROTACs.

Product Specifications

UNSPSC

12352203

Hazard Statement

H302-H315-H319-H335

Target

ADC Linker; PROTAC Linkers

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/boc-nh-peg3-c2-triazole-dbco-peg4-vc-pab-dmea.html

Solubility

10 mM in DMSO

Smiles

O=C(N1C2=CC=CC=C2C(N(CCOCCOCCOCCNC(OC(C)(C)C)=O)N=N3)=C3C4=CC=CC=C4C1)CCNC(CCOCCOCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC(C=C5)=CC=C5COC(N(C)CCNC)=O)=O)=O)=O)=O

Molecular Formula

C66H99N13O17

Molecular Weight

1346.57

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Shipping Conditions

Room temperature

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Alkyl/ether Linkers; Cleavable Linker; PEG Linkers; Protease Cleavable Linker

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