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MDPR (Boc) -Val-Cit-PAB

MDPR (Boc) -Val-Cit-PAB is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC) [1].

Product Specifications

CAS Number

[2281797-55-3]

UNSPSC

12352203

Hazard Statement

H302-H315-H319-H335

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mdpr-boc-val-cit-pab.html

Solubility

10 mM in DMSO

Smiles

O=C([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@@H](N1C(C=CC1=O)=O)CNC(OC(C)(C)C)=O)=O)=O)NC2=CC=C(CO)C=C2

Molecular Formula

C30H43N7O9

Molecular Weight

645.70

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]LYON, Robert, et al. SELF-STABILIZING LINKER CONJUGATES. WO2013173337.

Shipping Conditions

Room temperature

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Protease Cleavable Linker

Curated Selection

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