MDPR (Boc) -Val-Cit-PAB
MDPR (Boc) -Val-Cit-PAB is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC) [1].
Product Specifications
CAS Number
[2281797-55-3]
UNSPSC
12352203
Hazard Statement
H302-H315-H319-H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mdpr-boc-val-cit-pab.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@@H](N1C(C=CC1=O)=O)CNC(OC(C)(C)C)=O)=O)=O)NC2=CC=C(CO)C=C2
Molecular Formula
C30H43N7O9
Molecular Weight
645.70
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]LYON, Robert, et al. SELF-STABILIZING LINKER CONJUGATES. WO2013173337.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Protease Cleavable Linker
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