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Mps1-IN-4

Mps1-IN-4 is a selective Monopolar spindle 1 (Mps1) inhibitor with antiproliferative activity for cancer research[1].

Product Specifications

CAS Number

1263423-94-4

UNSPSC

12352005

Target

Mps1

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mps1-in-4.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1CC1)C(C=C2)=CC=C2C3=CN=C4N3N=C(NC(C)(C)C(F)(F)F)C=C4NCC5CCOCC5

Molecular Formula

C26H31F3N6O2

Molecular Weight

516.56

References & Citations

[1]Ken-Ichi Kusakabe, et al. Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity. J Med Chem. 2015 Feb 26;58 (4) :1760-75.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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