NNK-d3

NNK-d3 is the deuterium labeled NNK (HY-126477) [1][2].

Product Specifications

CAS Number

[86270-92-0]

UNSPSC

12352005

Hazard Statement

H301-H317

Target

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Solubility

10 mM in DMSO

Smiles

O=NN(C([2H])([2H])[2H])CCCC(C1=CN=CC=C1)=O

Molecular Formula

C10H10D3N3O2

Molecular Weight

210.25

Precautions

P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P405-P501

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Jin Z, et al. Tobacco-specific nitrosamine 4- (methylnitrosamino) -1- (3-pyridyl) -1-butanone promotes functional cooperation of Bcl2 and c-Myc through phosphorylation in regulating cell survival and proliferation. J Biol Chem. 2004;279 (38) :40209-40219.