Neochamaejasmine A
Neochamaejasmine A is a biflavonoid that can be isolated from the roots of Stellera chamaejasme L.. Neochamaejasmine A inhibits proliferation, induces cell cycle arrest and apoptosis in tumor cells. Neochamaejasmine A can be used in the research of cancers such as prostate cancer, hepatoma cancer[1][2].
Product Specifications
CAS Number
90411-13-5
UNSPSC
12352005
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/neochamaejasmine-a.html
Solubility
10 mM in DMSO
Smiles
O=C1[C@]([C@@]2([H])[C@@H](C3=CC=C(C=C3)O)OC4=CC(O)=CC(O)=C4C2=O)([H])[C@@H](C5=CC=C(C=C5)O)OC6=CC(O)=CC(O)=C61
Molecular Formula
C30H22O10
Molecular Weight
542.49
References & Citations
[1]Liu WK, et al. Involvement of p21 and FasL in induction of cell cycle arrest and apoptosis by neochamaejasmin A in human prostate LNCaP cancer cells. J Nat Prod. 2008 May;71 (5) :842-6. |[2]Ding Y, et al. Neochamaejasmin A Induces Mitochondrial-Mediated Apoptosis in Human Hepatoma Cells via ROS-Dependent Activation of the ERK1/2/JNK Signaling Pathway. Oxid Med Cell Longev. 2020 Jan 20;2020:3237150.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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