DTSSP Crosslinker
DTSSP Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
81069-02-5
UNSPSC
12352203
Hazard Statement
H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dtssp-crosslinker.html
Purity
98.87
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(ON1C(C(S(=O)(O)=O)CC1=O)=O)CCSSCCC(ON2C(C(S(=O)(O)=O)CC2=O)=O)=O
Molecular Formula
C14H16N2O14S4
Molecular Weight
564.54
Precautions
H315, H319, H335
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; Disulfide Cleavable Linker
Frequently Asked Questions
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