2-Hydroxy Ibuprofen
2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.
Product Specifications
CAS Number
51146-55-5
Product Name Alternative
(±) -2-Hydroxy Ibuprofen
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
COX
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/2-hydroxy-ibuprofen.html
Solubility
10 mM in DMSO
Smiles
O=C(O)C(C)C1=CC=C(CC(C)(O)C)C=C1
Molecular Formula
C13H18O3
Molecular Weight
222.28
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501
References & Citations
[1]Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61 (1) :2-7.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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