Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

2-Methylthio-AMP (diTEA)

2-Methylthio-AMP (2-MeSAMP) diTEA is a selective and direct P2Y12 antagonist. 2-Methylthio-AMP diTEA is an inhibitor of ADP-dependent platelet aggregation[1][2][3].

Product Specifications

CAS Number

[1227193-98-7]

Product Name Alternative

2-MeSAMP (diTEA) ; 2-Methylthioadenosine 5′-monophosphate (diTEA) ; 2-Methylthioadenosine 5′-phosphate (diTEA)

UNSPSC

12352005

Target

P2Y Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/2-methylthio-amp-ditea.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

O[C@H]1[C@@H](O)[C@H](N2C3=NC(SC)=NC(N)=C3N=C2)O[C@@H]1COP(O)(O)=O.CCN(CC)CC.CCN(CC)CC

Molecular Formula

C23H46N7O7PS

Molecular Weight

595.69

References & Citations

[1]John H Cleator, et al. Racial differences in resistance to P2Y12 receptor antagonists in type 2 diabetic subjects. J Pharmacol Exp Ther. 2014 Oct;351 (1) :33-43.|[2]Bernhard H Rauch, et al. Regulation of functionally active P2Y12 ADP receptors by thrombin in human smooth muscle cells and the presence of P2Y12 in carotid artery lesions. Arterioscler Thromb Vasc Biol. 2010 Dec;30 (12) :2434-42.|[3]A Malinin, et al. Validation of a VerifyNow-P2Y12 cartridge for monitoring platelet inhibition with clopidogrel. Methods Find Exp Clin Pharmacol. 2006 Jun;28 (5) :315-22.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

P2Y12 Receptor

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Recombinant Human IL2Ra / CD25 Protein (Fc tag)
E53A07419 50 µg

Recombinant Human IL2Ra / CD25 Protein (Fc tag)

Ask
View Details
INO80 (NM_017553) Human Tagged ORF Clone
RG212094 10 µg

INO80 (NM_017553) Human Tagged ORF Clone

Ask
View Details
MAFF (V-maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog F, hMafF, Transcription Factor MafF, U-Maf) (PE) discontinued
M1740-50-PE 200 µL

MAFF (V-maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog F, hMafF, Transcription Factor MafF, U-Maf) (PE) discontinued

Ask
View Details
PKC zeta Antibody
AF6405-01 100 µL

PKC zeta Antibody

Ask
View Details
PKC zeta Antibody
AF6405-02 200 µL

PKC zeta Antibody

Ask
View Details
2, ​4, ​7, ​9-​Tetramethyl-​5-​decyne-​4, ​7-​diol ethoxylate (Avg Mn 465-485)
420405-01 50 g

2, ​4, ​7, ​9-​Tetramethyl-​5-​decyne-​4, ​7-​diol ethoxylate (Avg Mn 465-485)

Ask
View Details