X-34

X-34 is a lipophilic and bright yellow-green fluorescent derivative of Congo red. X-34 can be used to stain neuritic and diffuse plaques, neurofibrillary tangles (NFTs), neuropil threads, and cerebrovascular amyloid in the brain. X-34 can be used for research of Alzheimer’s disease[1].

Product Specifications

CAS Number

215294-98-7

UNSPSC

12171500

Target

Amyloid-β; Fluorescent Dye

Type

Dye Reagents

Related Pathways

Neuronal Signaling; Others

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/x-34.html

Purity

96.47

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(O)C1=C(O)C=CC(/C=C/C2=CC=C(/C=C/C3=CC(C(O)=O)=C(O)C=C3)C=C2)=C1

Molecular Formula

C24H18O6

Molecular Weight

402.40

References & Citations

[1]Styren SD, et al. X-34, a fluorescent derivative of Congo red: a novel histochemical stain for Alzheimer's disease pathology. J Histochem Cytochem. 2000 Sep;48 (9) :1223-32.|[2]Link CD, et al. Visualization of fibrillar amyloid deposits in living, transgenic Caenorhabditis elegans animals using the sensitive amyloid dye, X-34. Neurobiol Aging. 2001 Mar-Apr;22 (2) :217-26.