A-1210477-piperazinyl
A-1210477-piperazinyl is a compound binds to protein myeloid cell leukemia 1 (MCL1) used for PROTAC technology[1].
Product Specifications
CAS Number
[2351218-72-7]
Product Name Alternative
PROTAC Mcl1-binding moiety 1
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/a-1210477-piperazinyl.html
Solubility
10 mM in DMSO
Smiles
O=C(C(N1CCN2CCNCC2)=C(CCCOC3=C4C=CC=CC4=CC=C3)C5=C1C(C6=C(COC7=CC=C(N8CCN(S(=O)(N(C)C)=O)CC8)C=C7)N(C)N=C6C)=CC=C5)O
Molecular Formula
C46H56N8O6S
Molecular Weight
849.05
References & Citations
[1]Papatzimas JW, et al. From Inhibition to Degradation: Targeting the Antiapoptotic Protein Myeloid Cell Leukemia 1 (MCL1) . J Med Chem. 2019 Jun 13;62 (11) :5522-5540.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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