Boc-NH-C6-amido-C4-acid
Boc-NH-C6-amido-C4-acid (PROTAC Linker 32) is an alkyl ether-based PROTAC linker can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[10436-21-2]
Product Name Alternative
PROTAC Linker 32
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-linker-32.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CCCCC(NCCCCCCNC(OC(C)(C)C)=O)=O
Molecular Formula
C17H32N2O5
Molecular Weight
344.45
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Targ. J Med Chem. 2019 Aug 21.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers
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