ASP1126
ASP1126 is a selective and orally active sphingosine-1-phosphate (S1P) agonist, with EC50 values of 7.12 nM, 517 nM for hS1P1 and hS1P3, respectively. ASP1126 decreases the number of peripheral lymphocytes, naive T cells, central memory T cells and effector memory T cells in the peripheral blood. ASP1126 has the potential to be applied in clinical transplantation with improved safety profile[1].
Product Specifications
CAS Number
[1228580-11-7]
UNSPSC
12352005
Target
LPL Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/asp1126.html
Solubility
10 mM in DMSO
Smiles
O=C(C1CCN(CC2=CC3=CC=C(OCC4=CC=C(OCC(F)(F)F)C(C(F)(F)F)=C4)C=C3OC2)CC1)O.[H]Cl
Molecular Formula
C26H26ClF6NO5
Molecular Weight
581.93
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-125881/ASP1126-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-125881/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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