KRAS G12C inhibitor 17
Product Specifications
UNSPSC Description
KRAS G12C inhibitor 17 is a potent KRAS G12C inhibitor extracted from patent WO2019110751A1, compound 82, has an IC50 of 5 nM[1].
Target Antigen
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein;MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-g12c-inhibitor-17.html
Solubility
10 mM in DMSO
Smiles
FC1=CC=CC(O)=C1C2=C(F)C(N=CC3=C4N5[C@H](CN(C(C=C)=O)[C@H](C)C5)CO3)=C4C=C2Cl
Molecular Weight
471.88
References & Citations
[1]Jason Grant Kettle, et al. Tetracyclic compounds as inhibitors of g12c mutant ras protein, for use as anti-cancer agents. WO2019110751A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-125875/KRAS-G12C-inhibitor-17-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-125875/
Clinical Information
No Development Reported
CAS Number
2349393-04-8
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