Glutathione Reductase, baker's yeast

Glutathione reductase, baker's yeast (EC 1.6.4.2) is a reductase. Glutathione reductase, baker's yeast eliminates intracellular ROS. Glutathione reductase, baker's yeast reduces oxidized glutathione (GSSG) to reduced glutathione (GSH) using NADPH as an electron donor. Glutathione reductase, baker's yeast exerts antioxidant activity. Glutathione reductase is mainly used to study diseases associated with oxidative stress, such as Parkinson's disease and sickle cell anemia[1][2][3].

Product Specifications

CAS Number

[9001-48-3]

Product Name Alternative

EC 1.6.4.2; GR

UNSPSC

12352204

Hazard Statement

H334

Target

Calcineurin; Reactive Oxygen Species (ROS)

Type

Enzyme

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/glutathione-reductase-baker-s-yeast.html

Solubility

10 mM in DMSO

Smiles

[GlutathioneReductase,baker'syeast]

Precautions

H334

References & Citations

[1]Couto N, et al. The role of glutathione reductase and related enzymes on cellular redox homoeostasis network. Free Radic Biol Med. 2016 Jun;95:27-42. |[2]ASUQUO E B. INHIBITORY EFFECT OF FLUOXETINE ON GLUTATHIONE REDUCTASE PURIFIED FROM BAKER’S YEAST.|[3]Dalmizrak O, et al. Mechanistic and structural insights into the in vitro inhibitory action of hypericin on glutathione reductase purified from baker's yeast. J Biochem Mol Toxicol. 2018 May;32 (5) :e22051.