CBM-301940
CBM-301940 (compound 5) is an orally active malonate CoA decarboxylase (MCD) inhibitor with IC50 value of 23 nM. CBM-301940 can be used in the study of cardiovascular diseases[1].
Product Specifications
CAS Number
902146-11-6
UNSPSC
12352005
Target
Malonyl-CoA Decarboxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/cbm-301940.html
Purity
99.80
Solubility
10 mM in DMSO
Smiles
CC(NC(C1=NOC(C(C(F)(F)F)(O)C(F)(F)F)C1)=O)CC(OC(C)(C)C)=O
Molecular Formula
C15H20F6N2O5
Molecular Weight
422.32
References & Citations
[1]Cheng JF, et al. Discovery of potent and orally available malonyl-CoA decarboxylase inhibitors as cardioprotective agents. J Med Chem. 2006 Jul 13;49 (14) :4055-8. doi: 10.1021/jm0605029. PMID: 16821767.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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