CBM-301940

CBM-301940 (compound 5) is an orally active malonate CoA decarboxylase (MCD) inhibitor with IC50 value of 23 nM. CBM-301940 can be used in the study of cardiovascular diseases[1].

Product Specifications

CAS Number

[902146-11-6]

UNSPSC

12352005

Target

Malonyl-CoA Decarboxylase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/cbm-301940.html

Purity

99.80

Solubility

10 mM in DMSO

Smiles

CC(NC(C1=NOC(C(C(F)(F)F)(O)C(F)(F)F)C1)=O)CC(OC(C)(C)C)=O

Molecular Formula

C15H20F6N2O5

Molecular Weight

422.32

References & Citations

[1]Cheng JF, et al. Discovery of potent and orally available malonyl-CoA decarboxylase inhibitors as cardioprotective agents. J Med Chem. 2006 Jul 13;49 (14) :4055-8. doi: 10.1021/jm0605029. PMID: 16821767.