LY-338979
LY-338979 (Pemetrexed 6-oxo diacid impurity) is a metabolite of LY231514 (Pemetrexed; HY-10820).
Product Specifications
CAS Number
193281-00-4
Product Name Alternative
Pemetrexed 6-oxo diacid impurity
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ly-338979.html
Purity
99.67
Solubility
10 mM in DMSO
Smiles
O=C(CC[C@H](NC(C1=CC=C(C=C1)CCC(C(N2)=O)C3=C2NC(N)=NC3=O)=O)C(O)=O)O
Molecular Formula
C20H21N5O7
Molecular Weight
443.41
Precautions
H302, H315, H319, H335
References & Citations
[1]Woodland JM, et al. Metabolism and disposition of the antifolate LY231514 in mice and dogs. Drug Metab Dispos. 1997 Jun;25 (6) :693-700.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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