Olanexidine (hydrochloride semihydrate)

Olanexidine hydrochloride semihydrate is an antibacterial agent. Olanexidine hydrochloride semihydrate is active against a wide range of bacteria, imcluding both Gram-positive and Gram-negative bacteria Olanexidine hydrochloride semihydrate is also an antiseptic. Olanexidine hydrochloride semihydrate can be used in the research of infection and inflammation[1][2][3].

Product Specifications

CAS Number

[218282-71-4]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/olanexidine-hydrochloride-semihydrate.html

Solubility

10 mM in DMSO

Smiles

N=C(NC(NCCCCCCCC)=N)NCC1=CC=C(C(Cl)=C1)Cl.O.[1/2].Cl

Molecular Formula

C17H27Cl2N5.ClH.1/2H2O

Molecular Weight

417.81

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Hagi A, et al. Bactericidal Effects and Mechanism of Action of Olanexidine Gluconate, a New Antiseptic. Antimicrob Agents Chemother. 2015 Aug;59 (8) :4551-9.|[2]Nakata H, et al. Effects of olanexidine gluconate on preoperative skin preparation: an experimental study in cynomolgus monkeys. J Med Microbiol. 2017 May;66 (5) :678-685.|[3]Imai K, et al. Disinfection efficacy and mechanism of olanexidine gluconate against norovirus. Am J Infect Control. 2022 Jul;50 (7) :764-771.|[4]Nii T, Yumoto H, Hirota K, Miyake Y. Anti-inflammatory effects of olanexidine gluconate on oral epithelial cells. BMC Oral Health. 2019 Nov 8;19 (1) :239.