Mycro1

Mycro1 is an inhibitor of c-Myc/Max dimer and DNA binding, with an IC50 value of 30 μM for the inhibition of Myc/Max DNA binding activity. Mycro1 can inhibit c-myc-dependent cell proliferation, gene transcription and oncogenic transformation[1].

Product Specifications

CAS Number

[313987-85-8]

UNSPSC

12352005

Target

C-Myc

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mycro1.html

Solubility

10 mM in DMSO

Smiles

O=C(NCC1=CC=C(C=C1)OC)C2=NN3C(C(F)(F)F)=CC(C4=CC=CS4)=NC3=C2

Molecular Formula

C20H15F3N4O2S

Molecular Weight

432.42

References & Citations

[1]Anke Kiessling, et al. Selective inhibition of c-Myc/Max dimerization and DNA binding by small molecules. Chem Biol. 2006 Jul;13 (7) :745-51.|[2]Kiessling A, et al. Selective inhibition of c-Myc/Max dimerization and DNA binding by small molecules. Chem Biol. 2006 Jul;13 (7) :745-51.