PNU-282987 (free base)
PNU-282987 (free base) is a potent α7 nicotinic acetylcholine receptor (nAChR) agonist with an EC50 of 154 nM. PNU-282987 (free base) is also a functional antagonist of the 5-HT3 receptor with an IC50 of 4541 nM. PNU-282987 (free base) can be used for the research of central and peripheral nervous systems[1].
Product Specifications
CAS Number
711085-63-1
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
5-HT Receptor; nAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pnu-282987-free-base.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@H]1CN2CCC1CC2)C3=CC=C(Cl)C=C3
Molecular Formula
C14H17ClN2O
Molecular Weight
264.75
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Lactoferrin
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Prostate Specific Antigen (PSA) (3E6), CF405S conjugate, 0.1mg/mL
