A201A
Product Specifications
CAS Number
37305-78-5
UNSPSC Description
A201A is a aminoacylnucleoside antibiotic with antibacterial activities. A201A is highly effective against Gram-positive and most Gram-negative anaerobic bacteria. A201A inhibits tRNA accommodation during translation[1][2].
Target Antigen
Antibiotic; Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/a201a.html
Solubility
10 mM in DMSO
Smiles
CN(C)C1=C(N=CN2[C@@H]3O[C@H](CO)[C@@H](NC(/C(C)=C/C4=CC=C(C=C4)O[C@@H]([C@@H](O)[C@@H]/5O)OC5=C(OC)\CO[C@@H]6[C@H]([C@H]([C@@H]([C@H](O6)C)OC)OC)O)=O)[C@H]3O)C2=NC=N1
Molecular Weight
802.82
References & Citations
[1]Nie S, et al. Total synthesis of nucleoside antibiotic A201A. J Am Chem Soc. 2014 Mar 19;136(11):4157-60.|[2]Wang J, et al. Bioinspired Total Synthesis of Complex Nucleoside Antibiotics A201A, A201D and A201E. Angew Chem Int Ed Engl. 2023 Jan 16;62(3):e202213810.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
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