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DiSBAC10

DiSBAC10 is a voltage-sensitive fluorescent probe used to study cell membrane electrical activity in FRET assays. In a resting polarized cell, DiSBAC10 resides on the outer leaflet of the membrane where it accepts photons from excited fluorescein-labeled proteins and re-emits the photons at a higher wavelength. Depolarization of the cell causes rapid translocation of DiSBAC10 to the inner leaflet of the membrane, thereby increasing the distance between fluorophores and reducing the FRET signal.

Product Specifications

CAS Number

169211-45-4

UNSPSC

12171500

Hazard Statement

H225, H319, H336

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/disbac10.html

Solubility

10 mM in DMSO

Smiles

O=C1/C(C(N(CCCCCCCCCC)C(N1CCCCCCCCCC)=S)=O)=C\C=C\C2C(N(CCCCCCCCCC)C(N(CCCCCCCCCC)C2=O)=S)=O

Molecular Formula

C51H88N4O4S2

Molecular Weight

885.40

Precautions

H225, H319, H336

Shipping Conditions

Room Temperature

Storage Conditions

Store at room temperature 3 years

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Frequently Asked Questions

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