2- (Biotin-amido) -1,3-bis- (C1-PEG1-acid)
2- (Biotin-amido) -13-bis (carboxylethoxy) propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[2086689-02-1]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-biotin-amido-1-3-bis-c1-peg1-acid.html
Solubility
10 mM in DMSO
Smiles
O=C1N[C@]2(CS[C@H]([C@]2(N1)[H])CCCCC(NC(COCCC(O)=O)COCCC(O)=O)=O)[H]
Molecular Formula
C19H31N3O8S
Molecular Weight
461.53
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
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