Entacapone acid

Entacapone acid (Tyrphostin AG1290) is a tyrosine kinase inhibitor. Entacapone acid reduces hepatic protein synthesis rate (HPS) in vivo[1].

Product Specifications

CAS Number

[160391-70-8]

Product Name Alternative

Tyrphostin AG1290

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

C-Met/HGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/entacapone-acid.html

Purity

98.86

Solubility

10 mM in DMSO

Smiles

O=C(/C(C#N)=C/C1=CC([N+]([O-])=O)=C(C(O)=C1)O)O

Molecular Formula

C10H6N2O6

Molecular Weight

250.16

Precautions

H302, H315, H319, H335

References & Citations

[1]Nakagohri T, et al. The effects of prostaglandin E1 and tyrosine kinase inhibitors on energy status and protein synthetic ability in hepatic ischemia-reperfusion injury. Surg Today. 1998;28 (5) :517-21.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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