Entacapone acid
Entacapone acid (Tyrphostin AG1290) is a tyrosine kinase inhibitor. Entacapone acid reduces hepatic protein synthesis rate (HPS) in vivo[1].
Product Specifications
CAS Number
160391-70-8
Product Name Alternative
Tyrphostin AG1290
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
C-Met/HGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/entacapone-acid.html
Purity
98.86
Solubility
10 mM in DMSO
Smiles
O=C(/C(C#N)=C/C1=CC([N+]([O-])=O)=C(C(O)=C1)O)O
Molecular Formula
C10H6N2O6
Molecular Weight
250.16
Precautions
H302, H315, H319, H335
References & Citations
[1]Nakagohri T, et al. The effects of prostaglandin E1 and tyrosine kinase inhibitors on energy status and protein synthetic ability in hepatic ischemia-reperfusion injury. Surg Today. 1998;28 (5) :517-21.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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