Trichodesmine
Product Specifications
UNSPSC Description
Trichodesmine is a dehydropyrrolizidine alkaloid. Trichodesmine can produces hepatotoxicty, pneumo- and neurotoxicity in vivo[1][2].
Target Antigen
Others
Type
Natural Products
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/trichodesmine.html
Solubility
10 mM in DMSO
Smiles
O=C(O[C@]1([H])CCN2[C@]1([H])C(CO3)=CC2)[C@H](C(C)C)[C@@](C)(O)[C@@](C)(O)C3=O
Molecular Weight
353.41
References & Citations
[1]Cooper RA, et, al. The relationship between reactivity of metabolites of pyrrolizidine alkaloids and extrahepatic toxicity. Proc West Pharmacol Soc. 1999;42:13-6.|[2]Pessoa CRM, et, al. Pulmonary and hepatic lesions caused by the dehydropyrrolizidine alkaloid-producing plants Crotalaria juncea and Crotalaria retusa in donkeys. Toxicon. 2013 Sep;71:113-20.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-12535/Trichodesmine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-12535/
Clinical Information
No Development Reported
CAS Number
548-90-3
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