Ro 41-0960
Ro 41-0960 is a selective catechol-O-methyltransferase (COMT) inhibitor[1].
Product Specifications
CAS Number
125628-97-9
UNSPSC
12352005
Target
COMT
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ro-41-0960.html
Purity
98.09
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(C1=CC([N+]([O-])=O)=C(C(O)=C1)O)C2=CC=CC=C2F
Molecular Formula
C13H8FNO5
Molecular Weight
277.20
References & Citations
[1]Storch A, et al. Catechol-O-methyltransferase inhibition attenuates levodopa toxicity in mesencephalic dopamine neurons. Mol Pharmacol. 2000 Mar;57 (3) :589-94.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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