Encainide (hydrochloride)

Encainide (MJ9067) hydrochloride is an antiarrhythmic agent with class IC activity. Encainide hydrochloride blocks voltage-dependent potassium channels. Encainide hydrochloride has the potential for life-threatening ventricular arrhythmias, symptomatic ventricular arrhythmias and supraventricular arrhythmias research[1][2].

Product Specifications

CAS Number

[66794-74-9]

Product Name Alternative

MJ9067 (hydrochloride)

UNSPSC

12352005

Hazard Statement

H301, H315, H319, H335

Target

Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/encainide-hydrochloride.html

Purity

98.0

Solubility

H2O : 1000 mg/mL (ultrasonic; warming; heat to 80°C)

Smiles

O=C(NC1=CC=CC=C1CCC2N(C)CCCC2)C3=CC=C(OC)C=C3.[H]Cl

Molecular Formula

C22H29ClN2O2

Molecular Weight

388.93

Precautions

H301, H315, H319, H335

References & Citations

[1]R N Brogden, et al. Encainide. A review of its pharmacological properties and therapeutic efficacy. Drugs. 1987 Nov;34 (5) :519-38.|[2]Hongliang Li, et al. Encainide, a class Ic anti-arrhythmic agent, blocks voltage-dependent potassium channels in coronary artery smooth muscle cells. Korean J Physiol Pharmacol. 2023 Jul 1;27 (4) :399-406.