KuWal151
KuWal151 is a CLK1, CLK2 and CLK4 inhibitor with a high selectivity margin towards DYRK kinases. KuWal151 has potent antiproliferative activity in an array of cultured cancer cell lines[1].
Product Specifications
CAS Number
2341841-06-1
UNSPSC
12352005
Target
CDK; DYRK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kuwal151.html
Solubility
10 mM in DMSO
Smiles
O=C1NCC2=C1C3=C(C=C2)C(C4=CC=CC(Cl)=C4)=CN3
Molecular Formula
C16H11ClN2O
Molecular Weight
282.72
References & Citations
[1]Walter A, et al. Molecular structures of cdc2-like kinases in complex with a new inhibitor chemotype. PLoS One. 2018 May 3;13 (5) :e0196761.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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