BRD5631
BRD5631 is an autophagy enhancer, enhances autophagy through an mTOR-independent pathway. BRD5631 affects several cellular disease phenotypes previously linked to autophagy, including protein aggregation, cell survival, bacterial replication, and inflammatory cytokine production[1].
Product Specifications
CAS Number
2446154-91-0
UNSPSC
12352005
Target
Autophagy
Type
Reference compound
Related Pathways
Autophagy
Applications
Cancer-programmed cell death
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/brd5631.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C2C(C(N(C[C@@H](OC)[C@@H](C)CN[C@@H](C)CO2)C)=O)=C1)C3=CC=C(C4=CC=CC=C4)C=C3
Molecular Formula
C30H35N3O4
Molecular Weight
501.62
References & Citations
[1]Kuo SY, et al. Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics. Proc Natl Acad Sci U S A. 2015 Aug 4;112 (31) :E4281-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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