Lupulone
Lupulone is a beta-acid from the hop plant H. lupulus with diverse biological activities including antibacterial, antioxidant, and anticarcinogenic properties[1][2][3].
Product Specifications
CAS Number
[468-28-0]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/lupulone.html
Purity
99.0
Solubility
DMSO : 40 mg/mL (ultrasonic; warming)
Smiles
O=C1C(C/C=C(C)\C)=C(C(C(CC(C)C)=O)=C(C1(C/C=C(C)\C)C/C=C(C)\C)O)O
Molecular Formula
C26H38O4
Molecular Weight
414.58
Precautions
H302, H315, H319, H335
References & Citations
[1]Tagashira M, et al. Antioxidative activity of hop bitter acids and their analogues. Biosci Biotechnol Biochem. 1995 Apr;59 (4) :740-2. |[2]Lamy V, et al. Lupulone, a hop bitter acid, activates different death pathways involving apoptotic TRAIL-receptors, in human colon tumor cells and in their derived metastatic cells. Apoptosis 13 (10), 1232-1242 (2008) .|[3]Bocquet L, et al. Phenolic Compounds from Humulus lupulus as Natural Antimicrobial Products: New Weapons in the Fight against Methicillin Resistant Staphylococcus aureus, Leishmania mexicana and Trypanosoma brucei Strains. Molecules. 2019 Mar 14;24 (6) :1024.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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