CMPD167
CMPD167 (MRK-1) is an orally active CCR5 inhibitor with potent antiviral activity in vitro[1].
Product Specifications
CAS Number
313994-79-5
Product Name Alternative
MRK-1
UNSPSC
12352005
Target
CCR; HIV
Type
Reference compound
Related Pathways
Anti-infection; GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cmpd167.html
Solubility
10 mM in DMSO
Smiles
CC(C)[C@H](C(O)=O)N([C@H]1C[C@H](CN2CCC(C3=CC(CC4=CC=CC=C4)=NN3CC)CC2)[C@@H](C5=CC=CC(F)=C5)C1)C
Molecular Formula
C35H47FN4O2
Molecular Weight
574.77
References & Citations
[1]Ronald S Veazey, et al. Protection of macaques from vaginal SHIV challenge by an orally delivered CCR5 inhibitor. Nat Med. 2005 Dec;11 (12) :1293-4.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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