Tec-IN-1
Tec-IN-1 (Compound 21) is a Tec inhibitor (IC50s of 11.7 μM) . Tec-IN-1 inhibits Tec-mediated tyrosine phosphorylation of FGF2, and inhibits FGF2 secretion from cells[1].
Product Specifications
CAS Number
931664-41-4
UNSPSC
12352005
Target
Tyrosinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tec-in-1.html
Solubility
10 mM in DMSO
Smiles
ClC1=CN=C(N=C(SCC(C2=C(C)C(C(C)=O)=C(C)N2)=O)N3)C3=C1
Molecular Formula
C16H15ClN4O2S
Molecular Weight
362.83
References & Citations
[1]La Venuta G, et al. Small Molecule Inhibitors Targeting Tec Kinase Block Unconventional Secretion of Fibroblast Growth Factor 2. J Biol Chem. 2016 Aug 19;291 (34) :17787-803.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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