Tec-IN-1

Tec-IN-1 (Compound 21) is a Tec inhibitor (IC50s of 11.7 μM) . Tec-IN-1 inhibits Tec-mediated tyrosine phosphorylation of FGF2, and inhibits FGF2 secretion from cells[1].

Product Specifications

CAS Number

931664-41-4

UNSPSC

12352005

Target

Tyrosinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tec-in-1.html

Solubility

10 mM in DMSO

Smiles

ClC1=CN=C(N=C(SCC(C2=C(C)C(C(C)=O)=C(C)N2)=O)N3)C3=C1

Molecular Formula

C16H15ClN4O2S

Molecular Weight

362.83

References & Citations

[1]La Venuta G, et al. Small Molecule Inhibitors Targeting Tec Kinase Block Unconventional Secretion of Fibroblast Growth Factor 2. J Biol Chem. 2016 Aug 19;291 (34) :17787-803.