KY-04031
KY-04031 is a potent PAK4 inhibitor with IC50 of 0.79 μM. KY-04031 binds to the ATP-binding pocket of PAK4. KY-04031 blocks tumor cell growth and invasion[1].
Product Specifications
CAS Number
[468056-29-3]
UNSPSC
12352005
Target
PAK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ky-04031.html
Solubility
10 mM in DMSO
Smiles
COC1=NC(NC2=CC3=C(NN=C3)C=C2)=NC(NCCC4=CNC5=C4C=CC=C5)=N1
Molecular Formula
C21H20N8O
Molecular Weight
400.44
References & Citations
[1]Byung Jun Ryu, et al. Discovery and the structural basis of a novel p21-activated kinase 4 inhibitor. Cancer Lett. 2014 Jul 10;349 (1) :45-50.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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