KY-04031
KY-04031 is a potent PAK4 inhibitor with IC50 of 0.79 μM. KY-04031 binds to the ATP-binding pocket of PAK4. KY-04031 blocks tumor cell growth and invasion[1].
Product Specifications
CAS Number
468056-29-3
UNSPSC
12352005
Target
PAK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ky-04031.html
Solubility
10 mM in DMSO
Smiles
COC1=NC(NC2=CC3=C(NN=C3)C=C2)=NC(NCCC4=CNC5=C4C=CC=C5)=N1
Molecular Formula
C21H20N8O
Molecular Weight
400.44
References & Citations
[1]Byung Jun Ryu, et al. Discovery and the structural basis of a novel p21-activated kinase 4 inhibitor. Cancer Lett. 2014 Jul 10;349 (1) :45-50.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb1882335 0.1 mg
Mouse RPSA Purified, clone RP-01 (Monoclonal) Antibody
Sign In for Pricing
View Details bs-8034R-PE-Cy5 100 µL
COMMD1 Polyclonal Antibody, PE-Cy5 Conjugated
Sign In for Pricing
View Details