OHM1
Product Specifications
UNSPSC Description
OHM1 is an analog of HIF1α CTAD that inhibits its binding with p300/CBP. OHM1 targets CH1 domain with an affinity of 0.53 μM[1].
Target Antigen
HIF/HIF Prolyl-Hydroxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ohm1.html
Solubility
10 mM in DMSO
Smiles
O=C(N)[C@@H](N1C([C@H](C)N(C([C@@H](N2C([C@H](CC(C)C)NCC2)=O)CC(C)C)=O)CC1)=O)CCC(N)=O
Molecular Weight
494.63
References & Citations
[1]Lao BB, et al. In vivo modulation of hypoxia-inducible signaling by topographical helix mimetics. Proc Natl Acad Sci U S A. 2014 May 27;111(21):7531-6.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-124722/OHM1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-124722/
Clinical Information
No Development Reported
CAS Number
1450995-09-1
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