CBK289001
CBK289001 is a tartrate-resistant acid phosphatase (TRAP/ACP5) inhibitor. CBK289001 inhibits TRAP 5bMV, TRAP 5bOX and TRAP 5aOX with IC50s of 125 μM, 4.21 μM and 14.2 μM, respectively[1].
Product Specifications
CAS Number
[1212663-24-5]
UNSPSC
12352005
Target
Protease Activated Receptor (PAR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cbk289001.html
Purity
99.74
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1[C@H](C2=NC(C3=CC=C(OCO4)C4=C3)=NO2)CC5=C(NC=N5)C1)NC(C)C
Molecular Formula
C19H20N6O4
Molecular Weight
396.40
References & Citations
[1]Anja Reithmeier, et al. Identification of inhibitors of Tartrate-resistant acid phosphatase (TRAP/ACP5) activity by small-molecule screening. Chem Biol Drug Des. 2018 Jul;92 (1) :1255-1271.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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