DS-6930
Product Specifications
UNSPSC Description
DS-6930 is a potent and selective agonist of PPARγ, with an EC50 of 41 nM. DS-6930 could robust reduce plasma glucose (PG), and with fewer PPARγ-related adverse effects than Rosiglitazone. DS-6930 can be used for the research of diabetes[1].
Target Antigen
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ds-6930.html
Solubility
10 mM in DMSO
Smiles
O=C(O)C1=CC=CC(OCC2=NC3=CC=C(OC4=NC=C(C)C=C4C)C=C3N2C)=C1
Molecular Weight
403.43
References & Citations
[1]Shinozuka T, et, al. Discovery of DS-6930, a potent selective PPARγ modulator. Part II: Lead optimization. Bioorg Med Chem. 2018 Oct 1;26(18):5099-5117.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-124581/DS-6930-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-124581/
Clinical Information
Phase 1
CAS Number
1242328-82-0
Curated Selection
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