Otosenine

Product Specifications

CAS Number

[16958-29-5]

UNSPSC Description

Otosenine is a natural pyrrolizidine alkaloid. Otosenine can be isolated from the aerial parts of the golden ragwort, Senecio aureus. Otosenine has spasmolytic and hypotensive properties[1][2].

Target Antigen

Others

Type

Natural Products

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/otosenine.html

Solubility

10 mM in DMSO

Smiles

O=C([C@]1(O[C@H]1C)C[C@@H](C)[C@]2(O)C)O[C@](C3=O)([H])CCN(C)C/C=C3/COC2=O

Molecular Weight

381.42

References & Citations

[1]Resch J F, et al. Otosenine from Senecio aureus[J]. Planta medica, 1983, 47(04): 255-255. |[2]Lee S, et al. Isolation and biological activity of azocine and azocane alkaloids. Bioorg Med Chem. 2022 Jan 15;54:116560.