2-Trifluoromethyl-2'-methoxychalcone

2-Trifluoromethyl-2'-methoxychalcone is a chalcone derivative. 2-Trifluoromethyl-2'-methoxychalcone is a potent Nrf2 activator. 2-Trifluoromethyl-2'-methoxychalcone can be used for oxidative stress and inflammation related diseases research[1].

Product Specifications

CAS Number

[1309371-03-6]

UNSPSC

12352005

Hazard Statement

H225, H319, H336

Target

Keap1-Nrf2

Type

Reference compound

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/2-trifluoromethyl-2-methoxychalcone.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=CC=C1OC)/C=C/C2=CC=CC=C2C(F)(F)F

Molecular Formula

C17H13F3O2

Molecular Weight

306.28

Precautions

H225, H319, H336

References & Citations

[1]Kumar V, et al. Novel chalcone derivatives as potent Nrf2 activators in mice and human lung epithelial cells. J Med Chem. 2011 Jun 23;54 (12) :4147-59.