Sibenadet (hydrochloride)
Product Specifications
UNSPSC Description
Sibenadet hydrochloride (AR-C68397AA) is a dual D2 dopamine receptor, beta2-adrenoceptor agonist with bronchodilator activity. Investigation in animal models of key chronic obstructive pulmonary disease (COPD) symptoms has demonstrated that Sibenadet hydrochloride effectively inhibits sensory nerve activity, thereby reducing reflex cough, mucus production and tachypnoea.
Target Antigen
Adrenergic Receptor; Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sibenadet-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
O=C1SC2=C(C=CC(O)=C2N1)CCNCCS(=O)(CCCOCCC3=CC=CC=C3)=O.[H]Cl
Molecular Weight
501.06
References & Citations
[1]Ind PW, Laitinen L, Laursen L, et al. Early clinical investigation of Viozan (sibenadet HCl), a novel D2 dopamine receptor, beta2-adrenoceptor agonist for the treatment of chronic obstructive pulmonary disease symptoms. Respir Med. 2003;97 Suppl A:S9-S21.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-124270/Sibenadet-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-124270/
Clinical Information
No Development Reported
CAS Number
154189-24-9
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