Sibenadet (hydrochloride)
Sibenadet hydrochloride (AR-C68397AA) is a dual D2 dopamine receptor, beta2-adrenoceptor agonist with bronchodilator activity. Investigation in animal models of key chronic obstructive pulmonary disease (COPD) symptoms has demonstrated that Sibenadet hydrochloride effectively inhibits sensory nerve activity, thereby reducing reflex cough, mucus production and tachypnoea.
Product Specifications
CAS Number
[154189-24-9]
Product Name Alternative
AR-C68397AA
UNSPSC
12352005
Target
Adrenergic Receptor; Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sibenadet-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
O=C1SC2=C(C=CC(O)=C2N1)CCNCCS(=O)(CCCOCCC3=CC=CC=C3)=O.[H]Cl
Molecular Formula
C22H29ClN2O5S2
Molecular Weight
501.06
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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