Pepticinnamin E
Pepticinnamin E is a Farnesyltransferase (FTase) inhibitor (IC50=42 µM) . Pepticinnamin E can be used in cancer and malaria research[1][2].
Product Specifications
CAS Number
147317-36-0
UNSPSC
12352005
Target
Farnesyl Transferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/pepticinnamin-e.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](N(C)C([C@@H](N(C([C@H](NC(/C=C/C1=CC=CC=C1/C=C\CCC)=O)CC2=CC=C(C=C2)O)=O)C)CC3=CC=C(C(O)=C3Cl)OC)=O)CC4=CC=CC=C4)OC[C@@H](N5)C(NCC5=O)=O
Molecular Formula
C49H54ClN5O10
Molecular Weight
908.43
References & Citations
[1]Hinterding K, et al. Synthesis and In Vitro Evaluation of the Ras Farnesyltransferase Inhibitor Pepticinnamin E. Angew Chem Int Ed Engl. 1998 May 18;37 (9) :1236-1239.|[2]Santa Maria KC, et al. Targeted Rediscovery and Biosynthesis of the Farnesyl-Transferase Inhibitor Pepticinnamin E. Chembiochem. 2019 Jun 3;20 (11) :1387-1393.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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