SCH54292
SCH54292 is a potent Ras-GEF interaction inhibitor with IC50 of 0.7 μM[1].
Product Specifications
CAS Number
188480-51-5
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sch54292.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C(NO)C=C1)(N([C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)CCOC3=CC=C4C=CC=CC4=C3)=O
Molecular Formula
C24H28N2O9S
Molecular Weight
520.55
Precautions
H302, H315, H319, H335
References & Citations
[1]A K Ganguly, et al. Interaction of a novel GDP exchange inhibitor with the Ras protein. Biochemistry. 1998 Nov 10;37 (45) :15631-7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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