Lobetyolinin

Lobetyolinin is a polyacetylene compound. Lobetyolinin can be extracted from the traditional Chinese medicine Codonopsis pilosula. Lobetyolinin has antiarrhythmic effects. Lobetyolinin can be used in liver cancer research[1][2].

Product Specifications

CAS Number

[142451-48-7]

UNSPSC

12352005

Target

Drug Derivative

Type

Natural Products

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Cancer; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/lobetyolinin.html

Purity

98.98

Solubility

Ethanol : 6.67 mg/mL (ultrasonic)

Smiles

C/C=C/C#CC#C[C@@H](O)[C@@H](/C=C/CCCO)O[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO

Molecular Formula

C26H38O13

Molecular Weight

558.57

References & Citations

[1]Liu H, et al. Screening and Identification of Cardioprotective Compounds From Wenxin Keli by Activity Index Approach and in vivo Zebrafish Model. Front Pharmacol. 2018;9:1288. Published 2018 Nov 13.|[2]Hu J, et al. Lobetyolin Suppresses the Proliferation of Hepatocellular Carcinoma through Activating DUSP1-ERK1/2 Signaling Pathway. Biol Pharm Bull. 2024;47 (10) :1751-1758.