HDAC-IN-69

HDAC-IN-69 (Compound 2) is a derivative of an HDAC inhibitor with inhibitory activity targeting maize histone deacetylase HD2[1].

Product Specifications

CAS Number

[676599-90-9]

UNSPSC

12352005

Hazard Statement

H302-H317-H318

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/apha-compound-8.html

Solubility

10 mM in DMSO

Smiles

CN1C=C(C=C1/C=C/C(NO)=O)C(CC2=CC=CC=C2)=O

Molecular Formula

C16H16N2O3

Molecular Weight

284.31

Precautions

P261-P264-P270-P272-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Ragno R, et al. 3- (4-Aroyl-1-methyl-1H-pyrrol-2-yl) -N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 3. Discovery of novel lead compounds through structure-based drug design and docking studies. J Med Chem. 2004 Mar 11;47 (6) :1351-9.