Antimalarial agent 20
Antimalarial agent 20 (Compound 49c) is an antimalarial agent with an IC50 of 0.6 nM against P. falciparum NF54 parasite strain in the NF54 albumax assay[1].
Product Specifications
CAS Number
1422207-75-7
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antimalarial-agent-20.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CC1=CC=CC=C1)[C@H](O)CN[C@@H](C2=CC=CC=C2)C)C3=CC=C(C(N4CCN(C)CC4)=O)C=C3
Molecular Formula
C31H38N4O3
Molecular Weight
514.66
References & Citations
[1]Ciana CL, et al. Novel in vivo active anti-malarials based on a hydroxy-ethyl-amine scaffold. Bioorg Med Chem Lett. 2013 Feb 1;23 (3) :658-62.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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